One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

A time-delay circuit enables precise control over the division of synthetic DNA droplets, which mimic biological Liquid-Liquid Phase Separation (LLPS) droplets found in cells. By utilizing a ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in  patients with an aggressive ...

Many cellular functions in the human body are controlled by biological droplets called Liquid-Liquid Phase Separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside ...