The gastrointestinal (GI) epithelium is the body’s first line of defense to luminal contents such as food, microbiota, pharmaceuticals, and toxins. A small pool of proliferative stem and progenitor ...

The intestine is responsible for absorbing nutrients while protecting the body from external aggression, a task performed by a complex intestinal barrier. Scientists from the Institut Pasteur ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.

Scientists have studied one ofd the most common laxatives in the world to reveal more about how the regulation of fluid flow ...

People with celiac disease must navigate everyday life by avoiding gluten, a protein in wheat, rye and barley which can trigger painful symptoms in the gut, impede the absorption of nutrients and ...

Nope, this isn’t a small, prickly mammal with a flashy dye job, but a single intestinal epithelial cell. The colorful, hairlike structures are microvilli, which are designed to maximize the cell’s ...