Heart

Negative exercise stress echocardiography and long-term outcomes: insights from a retrospective cohort study

Background Exercise stress echocardiography (ESE) is widely used to detect inducible myocardial ischaemia. However, a substantial proportion of ESEs remains inconclusive or shows abnormal ...
European Medical Journal

Plasma Presepsin Shows Promise as Mortality Predictor in Severe UTI

Can presepsin improve risk stratification in severe UTI? This study shows it outperforms standard biomarkers for mortality ...
Journal of Epidemiology and Community Health (JECH)

Scalable regionalised quality improvement model for ACS management in resource-limited primary healthcare facilities

Background Prehospital delays remain critical barriers to timely acute coronary syndrome (ACS) care, particularly for ...
BMJ

Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations ...

Objective To examine and summarise evidence from meta-analyses of cohort studies that evaluated the predictive associations between baseline cardiorespiratory fitness (CRF) and health outcomes among ...
BMJ Open

Clinical characteristics and outcomes of patients with type 2 diabetes mellitus and chronic kidney disease from two new-user medication cohorts: a retrospective cohort study ...

Objectives Given the rapidly evolving therapeutic landscape for type 2 diabetes (T2D) and chronic kidney disease (CKD), this study aimed to characterise the clinical profiles and real-world outcomes ...
BMJ Open

Development and validation of a risk prediction model for chronic kidney disease among adult hypertensive patients having follow-up at University of Gondar Comprehensive ...

Objective Chronic kidney disease (CKD) arises due to uncontrolled hypertension (HTN). HTN significantly increases the risk of complications in vital organs, mainly the kidneys. If hypertensive ...