A study in South Africa reveals that HIV was driving rapid changes in immunity gene frequencies before antiretroviral therapy (ART) became widely available, but this selective pressure has since been ...

Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...

A new study shows the virus could have doubled the frequency of genetic variants in a South African province if effective ...

A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions ...

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients. While the gene HLA-B*58:01 has long ...

A multi-institutional study led by a Massachusetts General Hospital (MGH) investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, ...

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients. While the gene HLA-B*58:01 has long ...

—Researchers provide the most comprehensive genetic synopsis of primary biliary cholangitis to date, identifying 44 risk-associated variants with strong evidence for novel genome-wide significant loci ...

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients. Subscribe to our newsletter for the ...

Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records Accurate human leukocyte antigen (HLA) typing is an essential step for designing ...