Intervertebral disk tissue was obtained from 35 patients undergoing surgery for chronic degenerative disease (n = 25) or an acutely herniated disk (n = 12). Of note, 48% of patients with degenerative ...

A promising new tissue engineering approach may one day improve outcomes for patients who have undergone discectomy - the primary surgical remedy for spinal disc herniations. Tested in live sheep for ...

The hierarchical structure of the intervertebral disc (approximately 45–55 mm diameter in the human lumbar spine and 2.5–5 mm in the rat coccygeal spine) is composed of the outer fiber-reinforced ...

Karin Wuertz-Kozak described her lab test equipment as a gym for cells. Stretching and compressions tests using bioreactors—her lab equipment—can make a difference in understanding how cells respond ...

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the ...

Therapies that target aging cells early pave the way to easing back pain. "Once intervertebral discs start to degenerate, there is very little regeneration that happens," says Dr. Risbud. "But our ...

Low back pain is the most prevalent musculoskeletal condition worldwide and is closely tied to the progressive degeneration of intervertebral discs. Aging remains the strongest risk factor for this ...

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal. As a result, the disc's ability to withstand ...

The Interfacial Biomaterials/Biomechanics Lab focuses on those healing phenomena that typically occur at a tissue material interface. While we must consider the ...

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal. As a result, the disc's ability to withstand ...