Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

For ion transport at nanoscale confinements, a cost of energy is discovered that originates from the rearrangement of the counter-ion shell, with the magnitude of which depending on the type of ...

Following this design principle, the researchers create angstrom-scale pores in bi-layer graphene sheets, and decorate the two pore edges with twisted rings of carbonyl groups. The artificial ion ...

Potassium channels are responsible for the selective permeation of K⁺ ions across cell membranes. K⁺ ions permeate in single file through the selectivity filter, a narrow pore lined by backbone ...

The study, published in Materials Today, details how these membranes could significantly improve energy efficiency and operational stability. Precisely engineered in both pore size and surface ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. Subscribe to our newsletter for the latest sci-tech news updates. Ion channels generate electrical ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...

Larger K+ (ionic radius: 1.3 Å) can selectively permeate larger Na + (ionic radius: 1.0 Å) through biological potassium ion channels, with selectivity ratios greater than 1000-fold. Scientists have ...