The Major Histocompatibility Complex is a genetic region characterized by a high density of genes, many of them involved in the immune response. Of considerable importance are the HLA class I and ...
Cattle possess a remarkable genetic diversity that underpins their adaptive immune responses and overall health. Central to this are the molecules encoded by the major histocompatibility complex (MHC) ...
It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...
The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...
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