The major histocompatibility complex (MHC) represents a critical gene family in vertebrates that shapes immune recognition and disease resistance through its extraordinary allelic diversity.
The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules.
The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...
It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...
Study explores whether female odor-based mating preferences could predict gamete-level compatibility
Major histocompatibility complex (MHC) genes are known to mediate sexual selection both at the individual and gamete level. Previous studies have shown that perceived body odor attractiveness is ...
Cattle possess a remarkable genetic diversity that underpins their adaptive immune responses and overall health. Central to this are the molecules encoded by the major histocompatibility complex (MHC) ...
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