Precision medicine models often rely on data from Northern European populations, leading to treatment inequities. Genetic diversity is crucial for understanding disease risk and treatment efficacy, as ...

Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move beyond one-time attacks and short-term memory to become a long-term immunity ...

Yusuf Roohani, PhD, machine learning group lead at the Arc Institute, is among a team of researchers training artificial intelligence (AI) models with transcriptome data to predict how cell gene ...

In the same vein as weather forecast models that predict developing storms, researchers have now developed a method to predict the cell activity in tissues over time. The new software combines ...

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

Microscopy image of a PGA at day 8 showing the early tissues supporting the embryo, including the amniotic sac and the yolk sac-like structures, surrounded by (extra-embryonic) mesoderm tissue.

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

The mystery of early embryonic communication is starting to be unraveled thanks to a new stem cell-based model.

Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...