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Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and ...

Researchers produce a precursor to tetrahydrocannabinol (THC) in amoebae with hopes to produce high yields of pure medicinal THC using biotechnology. A group at the Leibniz Institute for Natural ...

Researchers from the UCLA Henry Samueli School of Engineering and Applied Science have taken a major step forward in the field of metabolic engineering, successfully using the bacterium Escherichia ...

Researchers published a study confirming the discovery of a new process for producing active complex compounds in amoebae. In particular, studying the process of olivetolic acid production (a compound ...

Polyketides are a large class of secondary metabolites that have become indispensible in the modern medicine. They are made by massive enzymes called polyketide synthases, which contain multiple ...

Video shows the mechanism of action of a polyketide synthase module reported by a University of Michigan research team. A new study solves long-standing mysteries about how bacterial ...

Approach may produce tools to fight drug-resistant infections. You have full access to this article via your institution. Scientists have overcome an important hurdle in the race to develop new ...