Many biological functions and systems are influenced by how gene expression is spatially distributed, from subcellular through to tissue, organ, or at embryonic level. Our understanding of these ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper ...

Co-first author Jiyuan Yang, PhD, St. Jude Department of Computational Biology and co-senior and corresponding author Jiyang Yu, PhD, St. Jude Department of Computational Biology interim chair look at ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Spatial transcriptomics offers a revolutionary approach to understanding the tumor microenvironment (TME) in solid tumors by preserving the spatial context of gene expression, which is crucial for ...