Fc receptors for immunoglobulin G (FcγRs) link humoral and cellular immunity by binding antigen–IgG immune complexes and internalizing the complexes for efficient antigen presentation. FcγRs comprise ...

Asal Shirazi, Founder of ASA Foundation, shares insights into what drives inflammatory responses, including the role of ...

Human genetic variants associated with the development of systemic autoimmunity modulate B cell receptor (BCR) and co-receptor signalling, suggesting a role for dysregulated B cell signalling in ...

Chimeric antigen receptor (CAR) T-cell therapy for blood cancers appeared less toxic, and patients' hospital stays were days shorter, when they also had autoimmune disease before starting the ...

Please provide your email address to receive an email when new articles are posted on . The common consensus for some time has been that the prevalence of autoimmunity and autoimmune diseases has been ...

It also provides strong evidence that cross-reactivity between human and microbial proteins drives autoimmunity in at least two diseases and probably many others. Now that we understand the underlying ...

Scientists have revealed a novel mechanism through which the immune system controls autoimmunity and cancer. In the special focus of the researchers were regulatory T cells -- a type of white blood ...

Immune dysregulation is often defined as an immune response that is directed against one of the body’s own tissues, cells or molecules (e.g. autoimmunity) or against an innocuous foreign molecule that ...

Early exposure to complex dietary proteins may increase the risk of beta-cell autoimmunity and type 1 diabetes in children with genetic susceptibility. We tested the hypothesis that supplementing ...

The Comprehensive Arthritis, Musculoskeletal, Bone, and Autoimmunity Center (CAMBAC) is hosting a one-day regional symposium titled Advances in Musculoskeletal Infection Research: From Bench to ...

Chimeric antigen receptor (CAR) T-cell therapy for certain cancers comes with important side effects such as cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome. Use ...