Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane in many eukaryotic cells, including animal cells but not in plant cells or yeast. [1]

Jul 30, 2025 · Spectrin is a cytoskeletal protein that maintains the structural integrity of cells. It acts as a scaffold, particularly at the cell’s outer boundary, the plasma membrane.

Some spectrin isoforms are segregated to the soma and dendrites, and others are found in the axon and nerve terminal. β IV spectrin is concentrated within the axon initial segment (AIS) …

Spectrin is a large, cytoskeletal, and heterodimeric protein composed of modular structure of α and β subunits, it typically contains 106 contiguous amino acid sequence motifs called …

Spectrin is a large protein that functions as a primary structural element of the cell’s internal support system. It is a flexible, rod-like molecule that provides mechanical stability and shape …

Jan 25, 2023 · Clinical variants in four (SPTAN1, SPTBN1, SPTBN2 and SPTBN4) of the six spectrin genes expressed in the nervous system have been genetically and functionally linked …

This review discusses the spectrin superfamily of proteins that function to connect cytoskeletal elements to each other, the cell membrane, and the nucleus. The signature domain is the …